Searchable abstracts of presentations at key conferences in endocrinology

ea0035p818 | Paediatric endocrinology | ECE2014

Analysis of Th17 cells and IL17, IL23 cytokines in peripheral blood from children with autoimmune thyroid disease

Bossowski Artur , Moniuszko Marcin , Dabrowska Milena , Jeznach Marta , Rusak Malgorzata , Bossowska Anna

Up till now, altered balance of T helper 1 (Th1) and Th2 immune cells has been postulated to play an important role in the pathogenesis of autoimmune thyroid diseases (AITD). However, recent studies on thyroid diseases suggest a new role for Th17 (T helper 17) cells which have the ability to secrete cytokines: IL17, IL17F, IL21, and IL23. The aim of the study was to estimate the proporcions of circulating CD4+CD161+CD196+ and CD4+IL17+ Th17 cells and serum concentrations of IL...